They call all hours of the day. If I let the machine pick up, they don't leave a message. I have finally started picking up the phone and hanging it back up, not saying anything. Apparently they don't care, because they call me almost daily.

they call - I don't pick up - they never leave a message

Pick-up the phone and ask them to remove you from the calling list.  They are legally required to do so.  If you don't ask, they will continue to call...

Receiving calls from Courage Center that they will be in our area to pick up clothing items.

Although I do not answer this call, they just keep calling at all hours and all days.  They need to be stopped!!!!!!!!!!!!!!!!!!!!!!!!!!