I have been getting phone calls from 516-277-8421 every day now for almost a month.
Sometimes it comes up Glen Head, NY & sometimes it comes up as Animal League.
No one seems to be on the other end & it is becoming very annoying. Wish the calls would stop.

I looked North American Animal League up on Charity Navigator which is a non profit Charity Evaluator. They didn't have a very good write up. They aren't very transparent. They won't publish how much money is spent on the animals and how much goes in their pockets. Doesn't sound very trusting to me. I used to send them donations every month. Not anymore.

Actually, the DNC list does NOT prevent non-profit organizations from calling you.  They're exempt.

Received a call from this number at 8:50 pm.  Even for a non-profit, that's cutting it close to the 9pm deadline imposed by the FCC.  Furthermore, if it is the North Shore Animal League, I've told them previously I am not interested in donating but they still continue calling, as if hoping I might sustain a brain injury and forget I told them I'm not interested or they think they can wear me down.  This time, because I didn't recognize the number, I didn't say anything when I picked up the phone and the call quickly disconnected.  (I also use this tactic for calls I know will have a prerecorded message, like that eternally annoying Google placement scam. When the system doesn't hear anyone on the other end, it usually hangs up instead of playing its stupid message.  It doesn't stop them from calling again and again - they're going to do that anyway - but it spares me from having to listen to their nonsense.)
I have 'blacklisted' numbers from the North Shore Animal League (or whatever it's called) but they seem to keep calling from new numbers, which puts them in the spam column in my book.

This is NOT North Shore Animal League...they do not call to solicit donations...I asked when we were there to adopt our puppy....we ignore any call from any unknown number... and any charity that we decide to make a donation to is done by us calling them! That's the only way you can be sure who you are dealing with.