I too, have been getting these calls from this number relentlessly.  After reading all of your responses, I did call the number back and chose option 2 to opt out.

Exactly how does one 'opt out' by pressing '2' to a cell phone?

Its a company called Epik Relief they call from all different numbers, like 877-281-3050, and when you don't answer they call from another number.  When they leave a message they'll say you offer to get a lower rate for your credit card will expire or that they are trying to collect a debt. What ever you do, don't do it.. Don't even answer go and put them on the national block where they can't call you. Here's the web site, its a scam..
www.EpikRelief.com.. Hope this helps..I called the number back and they give the*67 201-918-4849 I blocked my number and they give you an option if you want to be put on the do not call list..

I have been getting a call from this number every half hour today. They hang up before you can answer it. I called it back and it was a customer service company???? It had a option to either talk to a rep. or press 2 to be taken off their call list, so I pushed 2. I have gotten 2 calls since then.
If anyone knows anything about this number Help

Yeah, I did answer this and it was something about getting a free pack to get government money. I eventually told them that I couldnt talk and didn't tell them when they could call me back, I was in a rush and I felt bad if I yelled at them. They called me 7 times in one hour today.